นิพนธ์ต้นฉบับพันธ์ทิพย์ เล่ม 9 Volume 50 หน้า 605 - 621.pmd

Objective Kidney stone disease has high rates of recurrence. In order to avert a recurrent episode, metabolic risk factors should be evaluated during follow-up. The study is aimed to investigate the metabolic abnormalities in patients with kidney stone and to explore whether metabolic disorders are associated with types of the stone. Methods A total of 34 patients with renal stone were recruited in the study and 24-hour urine and stone specimens were collected. Most patients (52 %) resided in the central region of Thailand. Thirty-two healthy controls participated and their 24-hour urine samples were also collected. Metabolic abnormalities including hypercalciuria, hyperoxaluria, hyperphosphaturia, hyperuricosuria, hypocitraturia, hypokaliuria and hypomagnesiuria were assessed. Urine volume and pH were also determined and the type of stone was analyzed using a Fourier transformed infrared spectrometry. นิพนธ์ต้นฉบับ